The ALS/MND Lab at the University of Malta uses the powerful Drosophila melanogaster (fruit fly) model system to uncover the genetic and molecular underpinnings of amyotrophic lateral sclerosis (ALS). Our goal is to understand disease mechanisms at a fundamental level and to pioneer novel therapeutic strategies for ALS.

We are currently seeking a highly motivated postdoctoral researcher to join our dynamic team for an exciting project focused on a newly identified gene associated with increased ALS risk (Rheenen et al. Nat Genet2021). In this project, you will develop and characterise Drosophila models with altered function of this gene, analysing ALS-relevant phenotypes and elucidating disease mechanisms through advanced cell biology techniques and multi-omics profiling of fly brain tissue.

For more about our lab and recent publications, please visit: http://staff.um.edu.mt/ruben.cauchi

Your Profile:

• A PhD in life sciences or biomedical sciences
• Strong background in genetics and molecular biology
• Experience working with model organisms, preferably Drosophila
• Proficiency in immunofluorescence imaging and cell biology techniques
• Highly motivated with excellent organisational and problem-solving skills
• Ability to work independently while thriving in a collaborative team environment
• Commitment to producing high-quality, publication-ready research
• Fluent in English with strong communication skills

What We Offer:

• Opportunity to work on cutting-edge ALS research in a supportive and collaborative environment
• Access to state-of-the-art facilities and technologies
• Mentorship and career development support
• The chance to contribute to impactful discoveries with translational potential

If you are interested in this post and you are passionate about neuroscience, genetics, and making meaningful contributions to ALS research, please contact lab head Prof. Ruben Cauchi enclosing CV (including publications).

The position is available immediately on a full-time basis for 24 months.